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Right now, we do not know what causes CFS. However, there does seem to be a family genetic history to it in some cases. We don’t know yet if this is just that the family is more susceptible, or that something in the genetic makeup is causing it.

There is also some research to suggest that some people who have CFS also have the Epstein-Barr virus (known to cause mononucleosis) or the Ross River virus (a debilitating virus which affects joints, making them painful and swollen).